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Influence of corporate lobbying in the security agencies. Assume that something is safe because approves the EFSA (European Food Safety Authority) or FDA (Food and Drug Administration) is to have much faith in the impartiality of these institutions and little knowledge of the pressure and influence of big food companies ( interesting report).
Moreover there is not even consensus among these agencies. Some additives (cyclamate, potassium bromate etc) are approved in the US and not in Europe or vice versa. What studies are better? What safety agency is more reliable ?.
There are few long-term studies in humans on additives. Most are performed with mice and are short lived, with individual additives.
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